IMGT Repertoire (IG and TR)

Alignment of alleles: house mouse (Mus musculus) TRAV8-2, TRAV8D-2 and TRAV8N-2

When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).
Dots indicate gaps according to the IMGT unique numbering.
Blanks at the 5' and/or 3' end indicate partial sequences.
Asterisk (*) in the sequence indicate a STOP-CODON.
Letters in red correspond to amino acids which are polymorphic in the other alleles.
Colours are according to Color menu for mutations, Color menu for sequence alignments and Color menu for splicing types.
The nucleotide (s) in bold and colored in purple (splicing frame 1) or green (splicing frame 2) from the DONOR splice site are added at the beginning of the following exon in order to obtain and to complete the first CODON of the DOMAIN or REGION resulting from the splicing site. These first CODONs are in bold and colored in purple (splicing frame 1) or green (splicing frame 2)
N (Asn, asparagine) of potential N-glycosylation sites (NXS/T, where X is different from P), (N-linked glycosylation) is shown in green
Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.
                                                                                                                               
                                               
                                                1   2   3   4   5   6   7   8   8A  9   10  11  12  13  14  15  16  17  18  19 
                                                S   Q   W   G   E   E   N   L       Q   A   L   S   I   Q   E   G   E   D   V  
  AC004096   TRAV8-2*01  F   V-REGION gDNA     agc caa tgg gga gaa gag aat ctt ... cag gct ctg agc atc cag gag ggt gaa gat gtt 

                                                                                                                               
  AE007512   TRAV8-2*01  F   V-REGION gDNA     --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                               
  AE008685   TRAV8-2*01  F   V-REGION gDNA     --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                               
  AC005855   TRAV8D-2*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --c 

                                                                                                                               
  AE007512   TRAV8D-2*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --c 

                                                                                                                               
  AE008684   TRAV8D-2*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --c 

                                                                                                                               
  AC161460   TRAV8N-2*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --c 

                                                                                                                               
  AC122813   TRAV8N-2*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --c 

                                                                                                                               
  IMGT000082 TRAV8N-2*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --c 

                                                                                                                               
  IMGT000082 TRAV8-2*02  P   V-REGION gDNA     --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --c 

                                                                                                                               
  U46581     TRAV8D-2*02 (F) V-REGION cDNA     --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --c 

                                                                                                                               
  AC163653   TRAV8D-2*03 F   V-REGION gDNA     --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --c 

                                                                                                                               
  IMGT000082 TRAV8D-2*03 F   V-REGION gDNA     --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --c 



                                                                           ___________________CDR1-IMGT____________________    
                                               
                                                20  21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39 
                                                T   M   N   C   S   Y   K   T   Y   T                               T   V   V  
  AC004096   TRAV8-2*01  F   V-REGION gDNA     acc atg aac tgc agt tac aag act tat aca ... ... ... ... ... ... ... act gtt gta 

                                                                                                                               
  AE007512   TRAV8-2*01  F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ... --- --- --- 

                                                                                                                               
  AE008685   TRAV8-2*01  F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ... --- --- --- 

                                                                                                                               
  AC005855   TRAV8D-2*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --c --- ... ... ... ... ... ... ... --- --- --t 

                                                                                                                               
  AE007512   TRAV8D-2*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --c --- ... ... ... ... ... ... ... --- --- --t 

                                                                                                                               
  AE008684   TRAV8D-2*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --c --- ... ... ... ... ... ... ... --- --- --t 

                                                                                                                               
  AC161460   TRAV8N-2*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --c --- ... ... ... ... ... ... ... --- --- --t 

                                                                                                                               
  AC122813   TRAV8N-2*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --c --- ... ... ... ... ... ... ... --- --- --t 

                                                                                                                               
  IMGT000082 TRAV8N-2*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --c --- ... ... ... ... ... ... ... --- --- --t 

                                                                                                                               
  IMGT000082 TRAV8-2*02  P   V-REGION gDNA     --- --- --- --- --- --- --- --- --c --- ... ... ... ... ... ... ... --- --- --t 

                                                                                                                               
  U46581     TRAV8D-2*02 (F) V-REGION cDNA     --- --- --- --- --- --- --- --- --c --- ... ... ... ... ... ... ... --- --- --t 

                                                                                                                               
  AC163653   TRAV8D-2*03 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ... --- --- --- 

                                                                                                                               
  IMGT000082 TRAV8D-2*03 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ... --- --- --- 



                                                                                                               _______________C
                                               
                                                40  41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59 
                                                H   W   Y   R   Q   D   S   G   R   G   P   A   L   I   I   L   I   R   S   N  
  AC004096   TRAV8-2*01  F   V-REGION gDNA     cac tgg tac agg caa gac tca ggc aga ggc ccg gcc ctg ata atc tta ata cgt tca aat 

                                                                                                                               
  AE007512   TRAV8-2*01  F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                               
  AE008685   TRAV8-2*01  F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                Q                   K           K                                              
  AC005855   TRAV8D-2*01 F   V-REGION gDNA     --g --- --- --a --g a-g --- --- -a- --- --t --- --- --- --- --- --- --- --- --- 

                                                Q                   K           K                                              
  AE007512   TRAV8D-2*01 F   V-REGION gDNA     --g --- --- --a --g a-g --- --- -a- --- --t --- --- --- --- --- --- --- --- --- 

                                                Q                   K           K                                              
  AE008684   TRAV8D-2*01 F   V-REGION gDNA     --g --- --- --a --g a-g --- --- -a- --- --t --- --- --- --- --- --- --- --- --- 

                                                Q                   K           K               Q   L                          
  AC161460   TRAV8N-2*01 F   V-REGION gDNA     --g --- --- --a --g a-g --- --- -a- --- --t --- -a- c-- --- --- --- --- --- --- 

                                                Q                   K           K               Q   L                          
  AC122813   TRAV8N-2*01 F   V-REGION gDNA     --g --- --- --a --g a-g --- --- -a- --- --t --- -a- c-- --- --- --- --- --- --- 

                                                Q                   K           K               Q   L                          
  IMGT000082 TRAV8N-2*01 F   V-REGION gDNA     --g --- --- --a --g a-g --- --- -a- --- --t --- -a- c-- --- --- --- --- --- --- 

                                                Q                   K           E           T       V                          
  IMGT000082 TRAV8-2*02  P   V-REGION gDNA     --g --- --- --a --g a-g --- --- ga- --- --t a-- --- g-- --- --- --- --- --- --- 

                                                Q                   K           K               Q   L                          
  U46581     TRAV8D-2*02 (F) V-REGION cDNA     --g --- --- --a --g a-g --- --- -a- --- --t --- -a- c-- --- --- --- --- --- --- 

                                                                                                                               
  AC163653   TRAV8D-2*03 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --t --- --- --- --- --- --- --- --- --- 

                                                                                                                               
  IMGT000082 TRAV8D-2*03 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --t --- --- --- --- --- --- --- --- --- 



                                               DR2-IMGT________________                                                        
                                               
                                                60  61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79 
                                                            E   R   E   K   R   S                       G   R   L   R   A   T  
  AC004096   TRAV8-2*01  F   V-REGION gDNA     ... ... ... gag cga gag aag cgc agt ... ... ... ... ... gga aga cta aga gcc acc 

                                                                                                                               
  AE007512   TRAV8-2*01  F   V-REGION gDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 

                                                                                                                               
  AE008685   TRAV8-2*01  F   V-REGION gDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 

                                                                                                                               
  AC005855   TRAV8D-2*01 F   V-REGION gDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --c --- --- --- 

                                                                                                                               
  AE007512   TRAV8D-2*01 F   V-REGION gDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --c --- --- --- 

                                                                                                                               
  AE008684   TRAV8D-2*01 F   V-REGION gDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --c --- --- --- 

                                                                                                                               
  AC161460   TRAV8N-2*01 F   V-REGION gDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --c --- --- --- 

                                                                                                                               
  AC122813   TRAV8N-2*01 F   V-REGION gDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --c --- --- --- 

                                                                                                                               
  IMGT000082 TRAV8N-2*01 F   V-REGION gDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --c --- --- --- 

                                                                                                                               
  IMGT000082 TRAV8-2*02  P   V-REGION gDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 

                                                                                                                               
  U46581     TRAV8D-2*02 (F) V-REGION cDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --c --- --- --- 

                                                                                                                               
  AC163653   TRAV8D-2*03 F   V-REGION gDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 

                                                                                                                               
  IMGT000082 TRAV8D-2*03 F   V-REGION gDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 



                                                                                                                               
                                               
                                                80  81  82  83  84 84A  85  86  87  88  89  90  91  92  93  94  95  96  97  98 
                                                L   D   T   S   S       Q   S   S   S   L   S   I   T   A   A   Q   C   E   D  
  AC004096   TRAV8-2*01  F   V-REGION gDNA     ctt gac acc tcc agc ... caa agt agc tct ctg tcc atc act gct gct cag tgt gaa gac 

                                                                                                                               
  AE007512   TRAV8-2*01  F   V-REGION gDNA     --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                               
  AE008685   TRAV8-2*01  F   V-REGION gDNA     --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                        G   T   L   A   T      
  AC005855   TRAV8D-2*01 F   V-REGION gDNA     --- --- --t --- --- ... --g --c --- --c --- --- --- --- -g- a-- -ta gc- ac- --- 

                                                                                                        G   T   L   A   T      
  AE007512   TRAV8D-2*01 F   V-REGION gDNA     --- --- --t --- --- ... --g --c --- --c --- --- --- --- -g- a-- -ta gc- ac- --- 

                                                                                                        G   T   L   A   T      
  AE008684   TRAV8D-2*01 F   V-REGION gDNA     --- --- --t --- --- ... --g --c --- --c --- --- --- --- -g- a-- -ta gc- ac- --- 

                                                                                                        G   T   L   A   T      
  AC161460   TRAV8N-2*01 F   V-REGION gDNA     --- --- --t --- --- ... --g --c --- --c --- --- --- --- -g- a-- -ta gc- ac- --- 

                                                                                                        G   T   L   A   T      
  AC122813   TRAV8N-2*01 F   V-REGION gDNA     --- --- --t --- --- ... --g --c --- --c --- --- --- --- -g- a-- -ta gc- ac- --- 

                                                                                                        G   T   L   A   T      
  IMGT000082 TRAV8N-2*01 F   V-REGION gDNA     --- --- --t --- --- ... --g --c --- --c --- --- --- --- -g- a-- -ta gc- ac- --- 

                                                                                                                               
  IMGT000082 TRAV8-2*02  P   V-REGION gDNA     --- --- --- --- --- ... --g --c --- --c --- --- --- --- --- --- --- --- --- --- 

                                                                                                        G   T   L   A   T      
  U46581     TRAV8D-2*02 (F) V-REGION cDNA     --- --- --t --- --- ... --g --c --- --c --- --- --- --- -g- a-- -ta gc- ac- --- 

                                                                                                                               
  AC163653   TRAV8D-2*03 F   V-REGION gDNA     --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                               
  IMGT000082 TRAV8D-2*03 F   V-REGION gDNA     --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- 



                                                                       ___CDR3-IMGT____
                                               
                                                99 100 101 102 103 104 105 106 107 
                                                T   A   V   Y   F   C   A   T   D  
  AC004096   TRAV8-2*01  F   V-REGION gDNA     act gct gtg tac ttc tgt gct aca gat g

                                                                                   
  AE007512   TRAV8-2*01  F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- -

                                                                                   
  AE008685   TRAV8-2*01  F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- -

                                                                                   
  AC005855   TRAV8D-2*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --t --- -

                                                                                   
  AE007512   TRAV8D-2*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --t --- -

                                                                                   
  AE008684   TRAV8D-2*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --t --- -

                                                                                   
  AC161460   TRAV8N-2*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --t --- -

                                                                                   
  AC122813   TRAV8N-2*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --t --- -

                                                                                   
  IMGT000082 TRAV8N-2*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --t --- -

                                                                                   
  IMGT000082 TRAV8-2*02  P   V-REGION gDNA     --- --- --- --- --- --- --- --t --- -

                                                                                T  
  U46581     TRAV8D-2*02 (F) V-REGION cDNA     --- --- --- --- --- --- --- --- acc 

                                                                                   
  AC163653   TRAV8D-2*03 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- -

                                                                                   
  IMGT000082 TRAV8D-2*03 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- -
This alignment of allele is generated by IMGT/OutilAllele (Mehdi Yousfi, Chantal Ginestoux, Perrine Pégorier and Patrice Duroux).
Created:: 05/09/2022
Last updated:: 22/09/2023
Authors:: Guilhem Zeitoun